Publications by authors named "A C Farney"

Article Synopsis
  • - The study investigates the impact of hepatic growth factor (HGF) on the secretion of small extracellular vesicles (sEV) from urine-derived stem cells (USCs), focusing on two methods of HGF delivery: bolus administration and controlled release using alginate microbeads.
  • - Results indicate that the group receiving HGF through controlled release from microbeads showed a significantly higher concentration of proteins and sEV compared to both the bolus and control groups after 7 days.
  • - The findings suggest that using a controlled release method for HGF significantly boosts sEV secretion from USCs, which could have implications for tissue regeneration and protection.
View Article and Find Full Text PDF

Introduction: The study purpose was to review retrospectively our single-center experience transplanting kidneys from deceased donors (DD) with acute kidney injury (AKI) according to terminal serum creatinine (tSCr) level.

Methods: AKI kidneys were defined by a doubling of the DD's admission SCr and a tSCr ≥ 2.0 mg/dL.

View Article and Find Full Text PDF

Background: Some patients with end stage renal disease are or will become narcotic-dependent. Chronic narcotic use is associated with increased graft loss and mortality following kidney transplantation. We aimed to compare the efficacy of continuous flow local anesthetic wound infusion pumps (CFLAP) with patient controlled analgesia pumps (PCA) in reducing inpatient narcotic consumption in patients undergoing kidney transplantation.

View Article and Find Full Text PDF

Background: The nonuse rate for kidneys recovered from deceased donors is increasing, rising to 27% in 2023. In 10% of these cases, 1 kidney is transplanted but the mate kidney is not.

Study Design: We conducted a retrospective, single-center cohort study from December 2001 to May 2023 comparing single kidneys transplanted at our center (where the contralateral kidney was not used) to kidneys where both were transplanted separately, at least 1 of which was at our center.

View Article and Find Full Text PDF

Introduction: There is limited experience transplanting kidneys from either expanded criteria donors (ECD) or donation after circulatory death (DCD) deceased donors with terminal acute kidney injury (AKI).

Methods: AKI kidneys were defined by a donor terminal serum creatinine level >2.0 mg/dL whereas non-ideal deceased donor (NIDD) kidneys were defined as AKI/DCD or AKI/ECDs.

View Article and Find Full Text PDF