Publications by authors named "A C Cortes-Marquez"
Article Synopsis
- Helicobacter pylori infections in children can reoccur after treatment, primarily through transmission within families, prompting a study on the genetic evolution of strains from two pediatric patients with recurrent infections.
- Researchers analyzed virulence genes and performed multilocus sequence typing (MLST) on strains, finding high genetic diversity, new alleles, and specific virulence genotypes frequently present in the strains.
- The study concluded that H. pylori strains undergo significant genetic changes during recrudescence and reinfection, possibly due to mutations and genetic recombination events, indicating a complex evolution in response to treatment and reinfection.
Differential expression of miRNA-146a and miRNA-155 in gastritis induced by Helicobacter pylori infection in paediatric patients, adults, and an animal model.
Ana Caren Cortés-Márquez Sandra Mendoza-Elizalde Francisco Arenas-Huertero Jimena Trillo-Tinoco Pedro Valencia-Mayoral
BMC Infect Dis
September 2018
Background: Helicobacter pylori is a major aetiologic agent associated with gastritis. H. pylori infections increase the expression of the Toll-like receptor (TLR), which in turn modulates the expression of microRNA (miRNA)-146a and miRNA-155.
View Article and Find Full Text PDFGenotypic differences in Helicobacter pylori play an important role in infection. We characterized the diversity of the cagA, cagE, babA2, and vacA genes in H. pylori strains isolated from pediatric patients and the relationship between these genes and clinical disease.
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