Publications by authors named "A C Chagas"

Reduced cerebral blood flow occurs early in the development of Alzheimer's disease (AD), but the factors producing this reduction are unknown. Here, we ask whether genetic and lifestyle risk factors for AD-the ε4 allele of the Apolipoprotein (APOE) gene, and physical activity-can together produce this reduction in cerebral blood flow which leads eventually to AD. Using in vivo two-photon microscopy and haemodynamic measures, we record neurovascular function from the visual cortex of physically active or sedentary mice expressing APOE3 and APOE4 in place of murine APOE.

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Background: There is no strong evidence demonstrating whether or not aerobic exercise in conjunction with resistance exercise improves metabolic diabetes markers in postmenopausal women.

Objective: To evaluate the effect of aerobic exercise and resistance training on metabolic markers in postmenopausal women with type 2 diabetes mellitus (T2DM) by means of a systematic review and meta-analysis.

Methods: The searches were completed using EMBASE, MEDLINE/PubMed, Scopus and Web of Science databases.

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Article Synopsis
  • Economic losses in livestock farming due to ticks are significant, with research focusing on plant extracts facing obstacles, particularly around formulation for effective use.
  • A study aimed to create a nanoformulation (AScn) using polycaprolactone nanoparticles and a hydrogel (ASlh) with xantan gum to enhance the efficacy and contact time of an extract against tick larvae.
  • Results showed the hydrogel (ASlh) significantly increased mortality of ticks at a concentration of 20 mg/mL, achieving 91.48% mortality, indicating its potential as a viable solution for tick control.
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Due to the negative impact of Haemonchus contortus in the tropics and subtropics, the detection of serum protein profiles that occur in infected sheep is of high relevance for targeted selective treatment strategies (TST). Herein, we integrated proteomics with phenotypic traits to elucidate physiological mechanisms associated to H. contortus infection in susceptible (Dorper - D) and resistant (Santa Inês - S) sheep breeds.

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