Publications by authors named "A C Bloomer"
Several therapeutic agents have been approved for treating multiple myeloma (MM), a cancer of bone marrow resident plasma cells. Predictive biomarkers for drug response could help guide clinical strategies to optimize outcomes. Here, we present an integrated functional genomic analysis of tumor samples from MM patients that were assessed for their ex vivo drug sensitivity to 37 drugs, clinical variables, cytogenetics, mutational profiles, and transcriptomes.
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- Scientists studied if drinking alcohol and smoking could affect how patients with colon cancer do after their diagnosis.
- They looked at 2,216 patients and checked if their drinking or smoking habits had any impact on getting sicker or dying from colon cancer during about 3 years of follow-up.
- The study found that drinking or smoking didn’t seem to affect their chances of getting worse with colon cancer, but it’s still important for survivors to avoid these habits to stay healthy overall.
Displaced intra-articular calcaneus fractures (DIACFs) are difficult injuries to treat and are often encountered by orthopedic surgeons. For DIACFs treated nonoperatively or with open reduction internal fixation (ORIF), a common complication is painful subtalar arthritis and the need for a secondary subtalar fusion, which prolongs the overall recovery time. One treatment option to address this sequela involves ORIF with subtalar fusion as the primary treatment.
View Article and Find Full Text PDFPurpose: Colorectal cancer (CRC) incidence and mortality are increasing among young adults (YAs) aged 18-39. This study compared quality of life (QOL) between YA and older adult CRC survivors in the ColoCare Study.
Methods: Participants were grouped by age (years) as follows: 18-39 (YA), 40-49, 50-64, and 65 + .
Objective: Opioid-related adverse drug events continue to occur. This study aimed to characterize the patient population receiving naloxone to inform future intervention efforts.
Design: We describe a case series of patients who received naloxone in the hospital during a 16-week time frame in 2016.