Publications by authors named "A C Babini"

Article Synopsis
  • The CHANGE survey aims to assess gender equity in rheumatology and gather physician insights on bullying, harassment, and equitable opportunities.
  • Launched in January 2023, the survey is a cross-sectional questionnaire available in six languages, targeting rheumatologists and healthcare professionals, with responses analyzed for gender-based discrimination.
  • This global initiative seeks to identify gender-related disparities in rheumatology to inform strategies for promoting inclusivity and equitable access to opportunities for all professionals in the field.
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Considerable variability exists in the way health-care providers treat patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in Latin America. The most frequently used treatments for ANCA-associated vasculitis are cyclophosphamide and prolonged glucocorticoid tapers; however, randomised controlled trials conducted over the past 30 years have led to the development of several evidence-based treatment alternatives for these patients. Latin America faces socioeconomic challenges that affect access to care, and the use of certain costly medications with proven efficacy ANCA-associated vasculitis is often restricted.

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Article Synopsis
  • The objective was to create the first evidence-based treatment guidelines for Takayasu arteritis (TAK) by the Pan American League of Associations for Rheumatology (PANLAR).
  • A panel of experts used a structured approach (PICO format) to develop key treatment questions, conducted a systematic literature review, and assessed evidence quality using GRADE methodology.
  • Eleven recommendations were made, including conditional support for oral glucocorticoids, certain immunosuppressants, and tumor necrosis factor inhibitors depending on the severity of the disease, along with recommendations for low-dose aspirin and surgical interventions during remission.
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Considerable variability exists in the way that health-care providers treat patients with giant cell arteritis in Latin America, with patients commonly exposed to excessive amounts of glucocorticoids. In addition, large health disparities prevail in this region due to socioeconomic factors, which influence access to care, including biological treatments. For these reasons, the Pan American League of Associations for Rheumatology developed the first evidence-based giant cell arteritis treatment guidelines tailored for Latin America.

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