Publications by authors named "A C A Heinzmann"
Article Synopsis
- This study aimed to understand how hereditary spastic paraplegias (HSP) affect bladder function and symptoms in patients.
- A retrospective review included 122 mostly male patients, revealing that bladder dysfunction typically starts later than motor issues and is linked to specific genetic mutations.
- The findings highlight that detrusor overactivity is common among these patients, indicating bladder issues often arise as mobility worsens.
Background: Meta-analyses indicate a high prevalence of burnout among medical students. Although studies have investigated different coping strategies and health interventions to prevent burnout, professional experience's influence on burnout resilience as seldom been explored. Therefore, in our study we aimed to examine the self-efficacy's mediating role in the relationship between past vocational training and burnout resilience.
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- The Scale for Assessment and Rating of Ataxia (SARA) is a key clinical tool for evaluating cerebellar ataxia but has received criticism regarding the relevance of its assessment items.
- A study involving 850 patients across different types of spinocerebellar ataxias (SCA1, SCA2, SCA3, SCA6) revealed significant differences in progression rates among cohorts, particularly with the EUROSCA cohort showing the fastest rates.
- The analysis found that not all items on the SARA scale contribute equally to measuring ataxia severity, and while some items are more sensitive to changes early or late in the disease, overall adjustments to the scale did not enhance responsiveness across different patient
Expanded CAG repeats in coding regions of different genes are the most common cause of dominantly inherited spinocerebellar ataxias (SCAs). These repeats are unstable through the germline, and larger repeats lead to earlier onset. We measured somatic expansion in blood samples collected from 30 SCA1, 50 SCA2, 74 SCA3, and 30 SCA7 individuals over a mean interval of 8.
View Article and Find Full Text PDFObjective: Every year, many applicants want to study medicine. Appropriate selection procedures are needed to identify suitable candidates for the demanding curriculum. Although research on medical school admissions has shown good predictive validity for cognitive selection methods (undergraduate GPA, aptitude tests), the literature on applicants with professional and/or academic experience prior to entering medical school remains slim.
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