Evaluation of the Effectiveness of Different Types of Professional Tooth Whitening: A Systematic Review.

Background/objectives: Tooth whitening is a cosmetic dental treatment that improves the color of natural teeth, making them whiter and brighter; this review aimed to evaluate the greater effectiveness of in-office, at-home, and combined bleaching with hydrogen or carbamide peroxide, also in relation to possible relapses and side effects (tooth sensitivity).

Methods: A literature search has been carried out through electronic databases, PubMed/MEDLINE, and Cochrane Library, focused on the use of the effectiveness of in-office, at-home, and combined dental bleaching. This review has been registered on PROSPERO (ID613248).

Selective metabolic regulations by p53 mutant variants in pancreatic cancer.

Background: Approximately half of all human cancers harbour mutations in the p53 gene, leading to the generation of neomorphic p53 mutant proteins. These mutants can exert gain-of-function (GOF) effects, potentially promoting tumour progression. However, the clinical significance of p53 GOF mutations, as well as the selectivity of individual variants, remains controversial and unclear.

Concordance and Clinical Outcomes Improvement Following Oral Hygiene Motivation: A Systematic Review and Report of the Workshop of the Italian Societies of Dental Hygiene.

A workshop on concordance and oral hygiene was held in February 2024. To address the topic, a systematic review aimed at investigating the effectiveness of motivational interventions in improving oral hygiene and focusing on periodontal clinical indices outcomes was designed. A comprehensive literature search was conducted across PubMed and Scopus electronic databases to identify relevant articles published up to 2024.

Laser and remineralising agents in dental erosion: a systematic review and meta-analysis.

Aim: This systematic review aimed to evaluate, by means of statistical comparison between selected studies, the effectiveness of laser irradiation on dental erosion applied alone or in combination with anti-erosive agents (fluoride, Acidulated phosphate fluoride APF and CPP-amorphous calcium fluoride phosphate CPP-ACFP), through optical profilometry and microhardness measurement.

Methods: The searching strategy was conducted according to the International PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, to answer research ques-tions regarding the effectiveness of lasers used in the context of dental erosion (such as Nd:YAG, CO2, Er:YAG, Er,Cr:YSGG, Diode, and Argon Ion lasers). A comprehensive and unrestricted sys-tematic searching was performed using the electronic databases of PubMed and Cochrane Library, for all articles published up to the end of January 2023.