Publications by authors named "A Bussmann"
Background: Mental disorders are complex diseases that affect 28% (about 17.8 million people) of the adult population in Germany annually. Since 2020, certain mobile health (mHealth) apps, so-called digital health applications (DiGA), are reimbursable in the German statutory health insurance system.
View Article and Find Full Text PDFWe investigate experimentally and numerically the interaction between a spherical cavitation bubble and a wall-bounded toroidal cavitation bubble. We demonstrate that shock wave focusing following toroidal bubble initiation induces the formation of micro-jets that pierce the spherical bubble in the torus-axis direction away from the surface, strongest in the anti-phase scenario. The velocity of micro-jets is determined by the initial standoff distance of the spherical bubble from the wall and thus from the toroidal bubble, with peak jet velocities approaching 1000m/s.
View Article and Find Full Text PDFArticle Synopsis
- A study was done at Londrina's University Hospital between November 2020 and July 2023, looking at pain and ulcers in patients with cutaneous leishmaniasis (CL).
- The researchers found that patients with CL felt less pain (2.60) compared to those with vascular skin ulcers (7.25).
- They discovered important details about the CL condition, like how it affects nerve fibers, which helps explain why CL patients have painless ulcers, making it easier for doctors to understand and treat them.
We reveal for the first time by experiments that within a narrow parameter regime, two cavitation bubbles with identical energy generated in antiphase develop a supersonic jet. High-resolution numerical simulation shows a mechanism for jet amplification based on toroidal shock wave and bubble necking interaction. The microjet reaches velocities in excess of 1000 m s^{-1}.
View Article and Find Full Text PDFArticle Synopsis
- Auto-injectors typically require refrigeration, and if not warmed, they may not deliver the full drug dose due to their mechanical design not compensating for changes in drug viscosity.
- A new piezoelectric micro diaphragm pump has been developed to effectively deliver high-viscosity liquids (up to 25 mPa·s) using a specialized design, achieving fluid pressures of up to 368 kPa.
- Experimental results show that this micropump can produce maximum flow rates of 2 mL/min through 27G needles, paving the way for more advanced auto-injectors capable of handling thick medications.