The rapid growth of the number of advanced Parkinson's disease (PD) patients has caused a significant increase in the use of device-aided therapies (DATs), including levodopa-carbidopa intestinal gel (LCIG) and continuous subcutaneous apomorphine infusion (CSAI). The objective of this study was to evaluate patients' satisfaction and the factors influencing preferences for CSAI and LCIG. The research focused on individuals diagnosed with advanced PD undergoing DAT at the Neurology Department of the University Hospital in Katowice.
View Article and Find Full Text PDFBackground: Ticks (Acari: Ixodida) pose a serious medical and veterinary threat as vectors of tick-borne pathogens. The wide variety of tick repellents available on the market primarily consist of synthetic preparations that may disrupt the ecological balance and accumulate in the environment, leading to harmful effects on humans and animals. The aim of the study was to develop an ecological preparation based on natural raw materials (biopolymers) with the addition of a mixture of essential oils that act as tick repellents.
View Article and Find Full Text PDFUnlabelled: Bronchiolitis is one of the main reasons for the hospitalization of young children. Based on updated recommendations, only supportive therapy is recommended for treatment. In Poland, many children that are hospitalized with bronchiolitis undergo a treatment that is not supported by current research.
View Article and Find Full Text PDFIntroduction And Objective: is one of the tick species of the greatest epidemiological importance in Europe. To date, the Eastern European and Western European populations of this tick species have been separated by an area located in Poland where the species has never been found. In this study, newly discovered localities in areas transformed by human activities in central-southern Poland are described.
View Article and Find Full Text PDFPhys Chem Chem Phys
February 2024
Monohydrated uracil (UW) complexes are stabilized by both O⋯HO and NH⋯O hydrogen bonds (H-bonds), simultaneously participating in forming three stable cyclic structures. The role and contribution of these individual H-bonds (O⋯HO and NH⋯O) to the stability of the three UW complexes are still not understood, because of the technical problems in obtaining their optimized structures by standard geometry optimization. The present study explores a non-standard approach to identify three single H-bonded local minima structures without imaginary frequency using DFT (M06-2X, B3LYP and B3LYP-D3), MP2 and CCSD(T) theories and Dunning's correlation-consistent aug-cc-pVTZ basis set, in both vacuum and aqueous media (CPCM method).
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