Publications by authors named "A Brzezinski"
Article Synopsis
- Perampanel (Fycompa) is an antiepileptic drug used to treat generalized seizures, but there's limited knowledge on how to handle overdoses, especially in kids.
- A case study describes a pediatric patient who experienced severe symptoms, including respiratory failure and coma, after ingesting a high dose of perampanel.
- Clinicians need to recognize overdose symptoms and be ready for immediate interventions like resuscitation, as there are no known reversal agents and the medication has a very long half-life of 105 hours.
Background: Total ankle arthroplasty (TAA) has become increasingly popular in the treatment for end-stage ankle arthritis in recent decades. However, there is limited evidence regarding the long-term clinical outcomes and complication rates of modern TAA implants.
Methods: This study presents a follow-up on a previous cohort involving 78 patients (81 ankles) who underwent Salto Talaris fixed-bearing TAA to treat end-stage arthritis, with a mean postoperative follow-up of 5.
Article Synopsis
- Elevated intracranial pressure (eICP) is a critical condition requiring quick detection, and traditional methods can be invasive and involve radiation.
- Ocular ultrasound offers a non-invasive way to detect optic disc elevation (ODE), which could serve as a useful marker for eICP.
- A review of 29 studies showed that ODE has good sensitivity (70-90%) and high specificity (up to 100%) in identifying eICP, suggesting it could improve diagnostic accuracy if further researched.
Purpose: The purpose of this study was to compare the biomechanics of 4-strand and 5-strand hamstring constructs for anterior cruciate ligament grafts.
Methods: Thirty-six human cadaveric hamstring grafts were tested in 3 different conditions: (1) graft femoral fixation complex, (2) graft femoral and tibial fixation (GFTF) complex using a human model, and (3) GFTF complex using a porcine model. Grafts were tested on a tensile testing machine.