Altered Intracerebellar Functional Connectivity in Friedreich's Ataxia: A Graph-Theory Functional MRI Study.

Historically, Friedreich's Ataxia (FRDA) has been linked to a relatively preserved cerebellar cortex. Recent advances in neuroimaging have revealed altered cerebello-cerebral functional connectivity (FC), but the extent of intra-cerebellar FC changes and their impact on cognition remains unclear. This study investigates intra-cerebellar FC alterations and their cognitive implications in FRDA.

A Deep Learning-Based Framework Oriented to Pathological Gait Recognition with Inertial Sensors.

Abnormal locomotor patterns may occur in case of either motor damages or neurological conditions, thus potentially jeopardizing an individual's safety. Pathological gait recognition (PGR) is a research field that aims to discriminate among different walking patterns. A PGR-oriented system may benefit from the simulation of gait disorders by healthy subjects, since the acquisition of actual pathological gaits would require either a higher experimental time or a larger sample size.

More Than the Sum of Its Parts: Disrupted Core Periphery of Multiplex Brain Networks in Multiple Sclerosis.

Disruptions to brain networks, measured using structural (sMRI), diffusion (dMRI), or functional (fMRI) MRI, have been shown in people with multiple sclerosis (PwMS), highlighting the relevance of regions in the core of the connectome but yielding mixed results depending on the studied connectivity domain. Using a multilayer network approach, we integrated these three modalities to portray an enriched representation of the brain's core-periphery organization and explore its alterations in PwMS. In this retrospective cross-sectional study, we selected PwMS and healthy controls with complete multimodal brain MRI acquisitions from 13 European centers within the MAGNIMS network.

Acute suppurative thyroiditis caused by Gemella Morbillorum: a case report.

Background: Acute suppurative thyroiditis (AST) is a rare form of thyroid inflammation prevalently of bacterial origin, that usually affects subjects with risk factors such as immunodeficiency, sepsis, and neck fistulas. The most prevalent pathogens associated with AST are gram-positive aerobic bacteria, followed by gram-negatives, while infections by anaerobic germs are exceptionally rare. Gemella morbillorum is a facultative anaerobic gram-positive bacterium that commonly populates the upper respiratory tract.