Publications by authors named "A Brownsdon"

Article Synopsis
  • The initiative aimed to engage children affected by cancer, survivors, families, and healthcare professionals to identify and prioritize research questions that could shape future studies on childhood cancer.
  • An online survey gathered over 1,200 potential questions, which were then refined and shortlisted through surveys and workshops with participants, resulting in a final consensus on the Top 10 priorities.
  • The most significant concern identified was the need for more effective and less burdensome treatments for children with cancer, emphasizing a focus on improving patient care and outcomes.
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Background: Consumer wrist-worn wearable activity monitors are widely available, low cost and are able to provide a direct measurement of several markers of physical activity. Despite this, there is limited data on their use in perioperative risk prediction. We explored whether these wearables could accurately approximate metrics (anaerobic threshold, peak oxygen uptake and peak work) derived using formalised cardiopulmonary exercise testing (CPET) in patients undergoing high-risk surgery.

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Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the literature and developed a clinical practice guideline that provides recommendations for ongoing communication methods for fertility preservation for patients who were diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger and their families.

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Purpose: Low recruitment of adolescents and young adults in cancer clinical trials is widely reported and may be linked to limited improvements in survival. Research to date does not adequately explain all underlying reasons for poor trial accrual. This paper reports health professional perceptions of communicating with adolescents and young adults with bone sarcoma about clinical trial participation.

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