Tracing Gadolinium levels throughout wastewater treatment: Insights from a yearly assessment in northern Spain.

Gadolinium (Gd) is a rare earth element (REE) used in the formulation of contrast agents for Magnetic Resonance Imaging (MRI) due to its paramagnetic properties. The growth in population and the improved quality of the healthcare systems over the last years, has promoted the use of MRI as an effective diagnostic tool thus increasing the consumption of gadolinium and its release into the wastewater treatment network. Therefore, the tracking and quantification of this metal in sewage treatment plants and water bodies, is of paramount importance since there are currently no specific rare earth treatment technologies installed in WWTPs, and consequently gadolinium is finally discharged into the environment.

[Subacute diseminated histoplasmosis in HIV patients].

Histoplasmosis is a cosmopolitan mycosis caused by Histoplasma capsulatum. It is endemic of Río de la Plata's riverbed and in immunocompromised patients may be deadly. We present two patients with Human Immunodeficiency Virus diagnosed with subacute disseminated histoplasmosis, which is a marker of Acquired Human Immunodeficiency Syndrome.

[Paraneoplastic dermatomyositis related to breast cancer: rare clinical association in two patients].

Paraneoplastic dermatomyositis is an inflammatory disease of the connective tissue that is caused by inmmunologic events in the presence of malignant tumors. It is more likely to happen in middle aged women and is related to ovarian, pancreatic, stomach and colon cancer and non Hogdkin lymphoma. We present two cases of dermatomyositis, with amyopathic origin associated to breast cancer.

[Post-irradiation morphea in brest cancer: a case report].

We report the case of a caucasian woman of 44 years old with no personal medical history. She was diagnosed breast carcinoma and underwent right partial mastectomy with adjuvant radiotherapy and chemotherapy. Four years after the intervention, presented a indurated plaque.

Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model.

The radioligand binding profiles and in vivo pharmacological characteristics of YM-44781, YM-44778 and YM-49598, novel non-peptide tachykinin receptor antagonists, were examined and compared to those of FK-888 and GR-159897. Since no functional NK(3) receptors were found in the rat bladder, the emphasis will be on the other two subtypes. YM-44781 and YM-49598 exhibited high binding affinities at NK(2) (pK(i) = 9.