Landslides are an important natural hazard in mountainous regions. Given the triggering and preconditioning by meteorological conditions, it is known that landslide risk may change in a warming climate, but whether climate change has already affected individual landslide events is still an open question, partly owing to landslide data limitations and methodological challenges in climate impact attribution. Here, we demonstrate the substantial influence of anthropogenic climate change on a severe event in the southeastern Alpine forelands with some estimated 952 individual landslides in June 2009.
View Article and Find Full Text PDFThe repeated expansion of East Asian steppe cultures was a key driver of Eurasian history, forging new social, economic, and biological links across the continent. Climate has been suggested as important driver of these poorly understood cultural expansions, but paleoclimate records from the Mongolian Plateau often suffer from poor age control or ambiguous proxy interpretation. Here, we use a combination of geochemical analyses and comprehensive radiocarbon dating to establish the first robust and detailed record of paleohydrological conditions for Lake Telmen, Mongolia, covering the past ~ 4000 years.
View Article and Find Full Text PDFClinical data from paired organs present a dependence structure that has to be considered when making statistical inference or evaluating classification rules with resampling-based techniques (bootstrap, cross-validation). We introduce a paired cross-validation approach for the estimation of misclassification error rates in the classification of data from paired organs. The dependence structure of the sample is honored by subject-level cross-validation.
View Article and Find Full Text PDFPurpose: The aim of this analysis was to evaluate the diagnostic usefulness of frequency doubling technology (FDT) perimetry and short-wavelength perimetry (SWAP). Moreover, to study a combination of both methods using the machine-learning technique double-bagging, which was recently established in glaucoma research.
Methods: Forty-three patients with "preperimetric" open-angle glaucoma (glaucomatous optic disc atrophy and no visual field defect in standard perimetry), 26 patients with "perimetric" open angle glaucoma (glaucomatous optic disc atrophy and visual field defect in standard perimetry), and 40 control subjects had FDT screening (protocol: C-20-5) and SWAP (Octopus 101, G2).
Objective: The aim of this study was to evaluate the longitudinal reproducibility of cartilage volume and surface area measurements in moderate osteoarthritis (OA) of the knee.
Materials And Methods: We analysed 5 MRI (GE 1.5T, sagittal 3D SPGR) data sets of patients with osteoarthritis (OA) of the knee (Kellgren Lawrence grade I-II).
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