Publications by authors named "A Brehm"

Background: There are limited therapeutic options in cases of failed reperfusion (modified thrombolysis in cerebral infarction [mTICI] score < 2b) after stent-retriever and/or aspiration based endovascular treatment (EVT) for acute ischemic stroke. Despite the absence of data supporting its use, rescue therapy (balloon angioplasty and/or stent implantation) is often utilized in such cases. Studies are limited to large vessel occlusions, while the outcomes and complications after rescue therapy in medium/distal vessel occlusions (MDVOs) have not been reported.

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  • * Using data from the National Ecological Observatory Network, the study focused on white-footed mice and found that individual factors such as sex, body mass, and reproductive status affected tick parasitism, with varying effects depending on the tick life stage.
  • * The research revealed that mouse movement behavior correlated with tick carrying rates, indicating that variations in host mobility could influence host-parasite encounters and potentially modify zoonotic disease risk due to changes in the environment and human activities.
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Importance: Acute respiratory failure (ARF) associated with antipsychotic use has been documented through case reports and population-based studies.

Objective: To assess whether the recent use of antipsychotics is associated with an increased risk of ARF in U.S.

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Background: The effect of endovascular therapy (EVT) on the outcome of stroke patients with a medium distal vessel occlusion (MDVO) is unclear. We report the results of MDVO patients treated with the 3 mm Trevo stent retriever (SR) and/or the AXS Catalyst 5 distal access catheter.

Methods: Data was derived from a prospective, multicenter global registry (ASSIST registry) which enrolled patients treated with operator preferred EVT technique at 71 sites from January 2019 to January 2022.

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  • * Data from 459 patients with vessel perforation showed a 90-day mortality rate of 51.9%, with only 16.3% achieving a favorable recovery (mRS 0-2).
  • * The findings indicate that large vessel perforation leads to worse outcomes, while thrombolysis doesn’t worsen prognoses; quick management of bleeding is crucial for survival.
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