Publications by authors named "A Breeden"
Affective science is a broad and burgeoning field, and the National Institutes of Health (NIH) support research on a similarly broad range of topics. Across NIH, funding is available for basic, translational, and intervention research, including research in non-human animals, healthy populations, and those with or at risk for disease. Multiple NIH Institutes and Centers have specific programs devoted to topics within the affective science umbrella.
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- Noninvasive brain stimulation (NIBS) shows promise for treating psychiatric and neurological issues, but its effectiveness varies among individuals.
- Targeting specific "hub" brain areas identified through individual brain networks may enhance the cognitive effects of NIBS interventions.
- Research indicates that inhibiting these hub areas disrupts cognitive functions, like working memory, more than targeting non-hub areas, suggesting the importance of individual brain network features in optimizing NIBS treatments.
Article Synopsis
- - The study investigates the link between callous unemotional (CU) traits in youths and the volume of the amygdala, which is believed to be dysfunctional in individuals with these traits and associated externalizing behaviors.
- - Assessing 148 youths through specific psychological inventories and brain imaging, researchers found that CU traits correlate with higher externalizing behaviors and reduced amygdala volume, primarily influenced by the callous and uncaring aspects of CU traits.
- - The results suggest that these callous-uncaring traits could mediate the connection between smaller amygdala volume and the severity of externalizing behaviors, highlighting the role of amygdala development in understanding conduct problems in youths.
Executive Dysfunction in Autism Spectrum Disorder Is Associated With a Failure to Modulate Frontoparietal-insular Hub Architecture.
Biol Psychiatry Cogn Neurosci Neuroimaging
September 2017
Article Synopsis
- Comorbid executive dysfunction in autism spectrum disorder (ASD) hinders adaptive functioning even when core symptoms improve, highlighting a need to focus on this area in ASD research.
- A study with 75 children (35 with ASD) found that typical developing children showed increased brain network adaptability during tasks, while children with ASD did not.
- The inability of certain brain regions to serve as adaptive hubs may underlie executive impairments in ASD, suggesting new avenues for understanding this condition and identifying potential biomarkers.