Publications by authors named "A Brazzale"
Background: Hypertensive crises in children represent critical medical situations characterized by severe hypertension and potential organ damage. Fenoldopam, a dopaminergic medication, offers a viable therapeutic option for managing such clinical scenarios. We aimed to evaluate efficacy and safety of fenoldopam in the management of hypertensive urgencies and emergencies.
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- Cutaneous malignant melanoma (CMM) is a common cancer among young people in wealthy countries, but there's limited research on its care quality and costs for adolescents and young adults (AYA).
- The study analyzed 2,435 CMM cases from a cancer registry in Italy, focusing on factors like age, clinical features, survival rates, and care costs.
- Findings revealed rising CMM incidence among AYAs, with males typically having less advanced cases, and those aged 15-39 showed better overall survival compared to older adults; however, care costs for AYAs were significantly lower.
Background: In industrialized countries, the aging population is steadily rising. The incidence of cutaneous malignant melanoma (CMM) is highest in old people. This study focuses on the clinicopathological profile of CMM and indicators of diagnostic-therapeutic performance in older patients.
View Article and Find Full Text PDFBackground: Soft tissue sarcomas (STS) are rare malignancies which prognosis varies significantly by primary site, histological subtype, and tumor stage. Their low incidence, and the complexity of their clinico-pathological characteristics demand standardized, cancer-tailored diagnostics and therapies managed at high-volume, multidisciplinary care centers. This study evaluates the quality of STS management in north-east Italy (Veneto Region) through a list of defined clinical indicators.
View Article and Find Full Text PDFThe Prevalent Comorbidome at the Onset of Psoriasis Diagnosis.
Dermatol Ther (Heidelb)
September 2023
Introduction: Psoriasis (PsO) is currently regarded as a systemic inflammatory disease with a growing burden of post-diagnosis associated comorbidities. To determine the initial burden of comorbiditis we evaluated the comorbidome at PsO onset.
Methods: In a matched case-control study, we extracted data on 57,228 patients and 125 morbidities from the Clalit Health Services Israeli insurance database.