Publications by authors named "A Bramos"
Importance: Advocates of laparoscopic surgery argue that all inguinal hernias, including initial and unilateral ones, should be repaired laparoscopically. Prior work suggests outcomes of open repair are improved by using local rather than general anesthesia, but no prior studies have compared laparoscopic surgery with open repair under local anesthesia.
Objective: To evaluate postoperative outcomes of open inguinal hernia repair under general or local anesthesia compared with laparoscopic repair.
Article Synopsis
- - Carpometacarpal joint osteoarthritis impacts 8-12% of people, and while surgery helps 78% of those not responding to other treatments, there's no clear agreement on the best surgical method; recent studies have looked at using acellular dermal matrices instead of traditional implants.
- - In a study using New Zealand rabbits, researchers compared implants of acellular dermal matrix and autologous tissue after removing the lunate carpal bones, analyzing the results through various histological techniques over 12 weeks.
- - Results showed that acellular dermal matrices led to significant increases in blood vessel formation in both the joint and subcutaneous areas, while autologous tissue did not show similar vascular growth; overall,
Impaired healing of the skin is a notable cause of patient morbidity and mortality. In diabetic individuals, dysregulated inflammation contributes to delayed wound healing. Specific immunomodulatory agents may have a role in the treatment of diabetic wounds.
View Article and Find Full Text PDFBackground: Fascia-wrapped diced cartilage grafts have become a useful tool in modern rhinoplasty surgery. Unfortunately, fascial harvest is associated with donor site morbidity; therefore, a nonautologous alternative to fascia would be ideal. Decellularized porcine mesothelium (PM), Meso BioMatrix™, is an acellular scaffold that could potentially fill this need.
View Article and Find Full Text PDFWound healing is significantly delayed in irradiated skin. To better understand global changes in protein expression after radiation, we utilized a reverse phase protein array (RPPA) to identify significant changes in paired samples of normal and irradiated human skin. Of the 210 proteins studied, fibronectin was the most significantly and consistently downregulated in radiation-damaged skin.
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