Publications by authors named "A Borowska"

Article Synopsis
  • ASCT2 is a crucial protein that exchanges neutral amino acids to maintain balance in cellular amino acid levels.
  • The research reveals that ASCT2 binds three sodium ions for each amino acid it transports and has unique mechanisms that prevent sodium ion leakage, differing from similar transporters like EAATs.
  • Unlike EAATs, ASCT2's rigid structure prevents it from switching to a mode that concentrates amino acids, keeping it functionally locked in an exchange mode.
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The aim of this study was to analyze the influence of factors on the results of 100-point judging systems, linear scoring and basic measurements, as well as differences between systems for dressage and jumping warmblood mares. The research covered official data on 1547 warmblood mares. Analysis of variance and phenotypic correlations (Pearson and partial) were used.

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Article Synopsis
  • A health education program was developed to study its impact on the quality of life of patients in forensic psychiatry wards, specifically those long-term isolated from their environment.
  • The research, conducted in Poland, involved 67 men diagnosed with schizophrenia, using assessments before and after the educational intervention to measure changes in quality of life and knowledge.
  • Results showed that while the program didn't significantly improve overall quality of life, it did enhance patients' knowledge and positively impacted their somatic condition.
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We consider parameter inference in cardio-mechanic models of the left ventricle, in particular the one based on the Holtzapfel-Ogden (HO) constitutive law, using clinical in vivo data. The equations underlying these models do not admit closed form solutions and hence need to be solved numerically. These numerical procedures are computationally expensive making computational run times associated with numerical optimisation or sampling excessive for the uptake of the models in the clinical practice.

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Combining biomechanical modelling of left ventricular (LV) function and dysfunction with cardiac magnetic resonance (CMR) imaging has the potential to improve the prognosis of patient-specific cardiovascular disease risks. Biomechanical studies of LV function in three dimensions usually rely on a computerized representation of the LV geometry based on finite element discretization, which is essential for numerically simulating in vivo cardiac dynamics. Detailed knowledge of the LV geometry is also relevant for various other clinical applications, such as assessing the LV cavity volume and wall thickness.

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