Publications by authors named "A Bondurand"

The FonSIDA is a private clinic created in 1992 within the premises of the National Blood Transfusion Center of Abidjan (CNTS), the largest city in Côte d'Ivoire. It provides medical and psychological follow-up for blood donors which are diagnosed as HIV-infected. This Centre provides blood for transfusions in Abidjan and the surrounding area, which from 1992 to 1999 collected 263,398 blood units.

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Human immunodeficiency virus (HIV)-associated bacillary angiomatosis has rarely been described in Africa. We report here the first case in Côte d'Ivoire. Although in industrialised countries bacillary angiomatosis has been described in patients with low CD4 count, this episode occurred in the first year following HIV-seroconversion in an adult patient with more than 500 CD4 cells per cubic millimetre.

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Article Synopsis
  • The study focused on the clinical and biological progression of HIV-1 among individuals in Abidjan, Côte d'Ivoire, involving 104 HIV-1-infected blood donors.
  • Most participants were asymptomatic at the start, with a median CD4 count indicating moderate immunosuppression and a high, stable viral load over the follow-up period of nearly 24 months.
  • The findings showed that while the majority remained AIDS-free and symptom-free for the first three years, there were still some instances of significant health events, such as tuberculosis and other infections.
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Objective: To evaluate nutritional status and dietary intakes in HIV-outpatients in Abidjan, Côte d'Ivoire.

Design: Cross-sectional study.

Setting: In the Outpatients and Counselling Unit in the University Hospital in Treichville, and in the follow-up Unit of Blood Donors.

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Peripheral blood mononuclear cells and lymphoid tissues from HIV-infected individuals display high levels of "tissue" transglutaminase (tTG) with respect to seronegative persons. In asymptomatic individuals, > 80% of the circulating CD4+ T cells synthesize tTG protein and the number of these cells matches the level of apoptosis detected in the peripheral blood mononuclear cells from the same patients. In HIV-infected lymph nodes tTG protein is localized in large number of cells (macrophages, follicular dendritic cells, and endothelial cells), showing distinctive morphological and biochemical features of apoptosis as well as in lymphocytes and syncytia.

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