Publications by authors named "A Bolsi"
Article Synopsis
- The study evaluated craniospinal irradiation (CSI) treatments using protons at the Paul Scherrer Institute, focusing on local recurrences and late toxicity outcomes for 71 patients, mostly children and young adults with tumors like medulloblastoma and ependymoma.
- Data from patients treated in both prone and supine positions were analyzed, revealing that supine positioning led to lower systematic and random errors in treatment setup, resulting in more accurate dosing.
- The research concluded that local failures in treatment were not linked to inaccuracies in radiation dosing, and there was no observed correlation between treatment-related toxicities and increased radiation effects.
This study presents the first clinical implementation of an efficient online daily adaptive proton therapy workflow (DAPT).The DAPT workflow includes awhere aand aare optimized on the planning computed tomography (CT). In the, theis re-optimized on daily images from an in-room CT.
View Article and Find Full Text PDFBackground And Purpose: As no guidelines for pencil beam scanning (PBS) proton therapy (PT) of paediatric posterior fossa (PF) tumours exist to date, this study investigated planning techniques across European PT centres, with special considerations for brainstem and spinal cord sparing.
Materials And Methods: A survey and a treatment planning comparison were initiated across nineteen European PBS-PT centres treating paediatric patients. The survey assessed all aspects of the treatment chain, including but not limited to delineations, dose constraints and treatment planning.
Purpose: To investigate the current practice patterns in image-guided particle therapy (IGPT) for cranio-spinal irradiation (CSI).
Methods: A multi-institutional survey was distributed to European particle therapy centres to analyse all aspects of IGPT. Based on the survey results, a Delphi consensus analysis was developed to define minimum requirements and optimal workflow for clinical practice.