The Efficacy and Tolerability of a Fixed Combination of Perindopril and Indapamide in the Treatment of Unregulated Essential Hypertension - a Postmarketing Study.

Objective: The objective of this non-interventional post-marketing clinical trial was to analyze the antihypertensive effect and safety of a fixed combination of perindopril and indapamide in the treatment of unregulated essential hypertension.

Patients And Methods: The prospective clinical trial included patients aged 20 to 75 years with essential hypertension and blood pressure values ≥ 140/90 mmHg at baseline. On the basis of the investigator's decision, patients received 2 mg perindopril + 0.

Benefits of abdominal paracentesis drainage performed ahead of percutaneous catheter drainage as a modification of the step-up approach in acute pancreatitis with fluid collections.

Aim: The aim of the study is to evaluate the role of abdominal paracentesis drainage (APD) ahead of percutaneous catheter drainage (PCD), as a modification of the step-up approach, when treating acute pancreatitis (AP) with peritoneal ascitic fluid (PAF).

Patients And Methods: This is a prospective cohort study including 118 participants with AP in which the indicative factors for upgrading from APD to PCD were investigated in patients with PAF. Ninety six patients with a sufficient volume of PAF initially underwent ultrasound-guided APD and were separated into two groups : group A (the patients who did not undergo PCD after APD) and B (the patients who underwent PCD after APD).