Publications by authors named "A Bofill"
Background: Azithromycin has been shown to be beneficial in preventing infectious diseases, including malaria, infectious diarrhoea and pneumonia. A cluster randomised control trial on azithromycin MDA in children in Niger, Malawi and Tanzania found a reduction in all-cause under-five (U5) mortality in communities who received azithromycin compared to placebo. However, the reduction was largest and statistically significant only in Niger.
View Article and Find Full Text PDFUnlabelled: Urolithiasis corresponds to the formation of stones in the urinary tract. It is a multifactorial metabolic disorder; its formation is related to oxidative stress and inflammatory processes. The mitochondria, for its part, is an intracellular organelle that plays a role in the regulation of intracellular oxidative stress and intracellular calcium homeostasis, both processes related to urolithiasis.
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- This study examines how using Magnetic Resonance Cholangiopancreatography (MRCP) can help identify disconnected pancreatic duct syndrome (DPDS) in patients with walled-off necrosis (WON) to prevent the recurrence of pancreatic fluid collections (PFCs).
- In the research, 121 patients were assessed, with those who had MRCP showing a significantly lower recurrence rate of PFCs (0%) compared to those who did not have MRCP (16.8%).
- The findings suggest that MRCP is effective in identifying patients at risk for recurrence, enabling better management strategies and preventing subsequent PFC occurrences.
Biliary tract complications are an important cause of morbidity and mortality after liver transplantation (LT) occurring in 5% to 25% of patients. The most common biliary complication in LT recipients are strictures representing approximately half of these biliary adverse events. Bile duct strictures can be divided into anastomotic biliary strictures (ABS) and non-anastomotic biliary strictures (NABS) depending on their location in the biliary tree, being ABS the most encountered type.
View Article and Find Full Text PDFBackground: Endoscopic retrograde cholangiopancreatography (ERCP) within 72 h is suggested for patients presenting with acute biliary pancreatitis (ABP) and biliary obstruction without cholangitis. This study aimed to identify if urgent ERCP (within 24 h) improved outcomes compared to early ERCP (24-72 h) in patients admitted with predicted mild ABP.
Methods: Patients admitted for predicted mild ABP defined as a bedside index of severity in acute pancreatitis score < 3 and underwent ERCP for biliary obstruction within 72 h of presentation during the study period were included.