Publications by authors named "A Bleuzen"

Article Synopsis
  • The study aimed to explore the characteristics of Systemic sclerosis (SSc) patients experiencing sicca symptoms, by analyzing major salivary glands through ultrasound, minor salivary gland biopsies, and clinical evaluations, while comparing these to patients with Sjögren's Disease (SjD) and other causes of sicca symptoms.
  • A total of 60 SSc patients with sicca symptoms and additional groups including SSc patients without symptoms and SjD patients were examined, revealing that many SSc patients showed objective abnormalities in salivary gland function, even if they didn't report symptoms.
  • The findings indicated that SjD-SSc patients had more severe salivary gland involvement compared to those with isolated conditions, highlighting the need for future
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Article Synopsis
  • RECIST criteria for assessing cancer therapy response, especially for bevacizumab, are often insufficient compared to new radiological biomarkers like tumor-to-liver density (TTLD) ratio and modified size-based criteria.
  • A study analyzing 79 out of 137 colorectal cancer liver metastases (CRLM) patients found that a TTLD ratio greater than 0.6 at baseline was a significant predictor for longer progression-free and overall survival, while tumor size reduction did not correlate with TTLD variations.
  • The findings support the use of TTLD ratio as an early indicator of long-term clinical outcomes and its association with improved perfusion parameters in patients undergoing treatment.
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Background: Visceral fat produces angiogenic factors such as vascular endothelial growth factor that promote tumoral growth. However, its influence on outcome for patients with advanced cancer treated with anti-angiogenic agents is controversial.

Aims: The aim of this study was to determine whether visceral fat volume, visceral fat area and body mass index are associated with outcome in patients receiving first-line bevacizumab-based treatment for metastatic colorectal cancer.

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The magnetic properties of a series of trimetallic (Co,Ni)Fe Prussian blue analogues (PBAs) were investigated by SQUID magnetometry and X-ray magnetic circular dichroism (XMCD) at the three transition metal (TM) K-edges. In turn, the PBA trimetallic series was used as a tool in order to better understand the information contained in TM K-edge XMCD and particularly the chemical nature of the probed species (extended sub-lattice or localized entities). The results show that the magnetic behavior of the compounds is dictated by competing exchange interactions between the Co-Fe and Ni-Fe pairs, without spin frustration.

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The potassium hexacyanoferrate(III), K[Fe(CN)], is known for its exceptional magnetic anisotropy among the 3d transition metal series. The Fe(III) ions are in the = 1/2 low spin state imposed by the strong crystal field of the cyanido ligands. A large orbital magnetic moment is expected from previous publications.

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