Publications by authors named "A Blaschke"
Article Synopsis
- The study examines the effectiveness of antibiotics in treating pediatric pneumonia in children and adolescents, specifically comparing outcomes for those who received antibiotics versus those who did not.
- Data was collected from a multistate claims database for Medicaid-insured individuals under 17 years old who were diagnosed with pneumonia between 2017 and 2019, taking into account factors to minimize bias.
- Results showed that treatment failure rates were slightly higher in children who did not receive antibiotics (10.7%) compared to those who did (8.7%), although the difference was not clinically significant.
A significant hurdle in untargeted lipid/metabolomics research lies in the absence of reliable, cross-validated spectral libraries, leading to a considerable portion of LC-MS features being labeled as unknowns. Despite continuous advancement in annotation tools and libraries, it is important to safeguard, publish and share acquired data through public repositories. Embracing this trend of data sharing not only promotes efficient resource utilization but also paves the way for future repurposing and in-depth analysis; ultimately advancing our comprehension of Covid-19 and other diseases.
View Article and Find Full Text PDFMicroplastics in urban runoff undergo rapid fragmentation and accumulate in the soil, potentially endangering shallow groundwater. To improve the understanding of microplastic transport in groundwater, column experiments were performed to compare the transport behavior of fragmented microplastics (FMPs ∼1-µm diameter) and spherical microplastics (SMPs ∼1-, 10-, and 20-µm diameter) in natural gravel (medium and fine) and quartz sand (coarse and medium). Polystyrene microspheres were physically abraded with glass beads to mimic the rapid fragmentation process.
View Article and Find Full Text PDFThe contribution of ships to the microbial faecal pollution status of water bodies is largely unknown but frequently of human health concern. No methodology for a comprehensive and target-orientated system analysis was available so far. We developed a novel approach for integrated and multistage impact evaluation.
View Article and Find Full Text PDFArticle Synopsis
- Viral bronchiolitis is a common illness in kids, and while treatment is mainly supportive, some may have serious bacterial infections (cSBIs) that require antibiotics; identifying these infections can be tricky.
- A study conducted at a children's hospital from 2012 to 2019 looked at children under 2 with bronchiolitis, finding that 4.2% had at least one cSBI, primarily bacterial pneumonia.
- Factors increasing the risk of cSBI included needing invasive mechanical ventilation, high C-reactive protein levels, having complex chronic conditions, and being admitted to the PICU.