The spaceflight conditions lead to disturbances in immune system and cause the changes in microbial and chemical environment that create preconditions for immunodeficiency and allergic disease development. With the spaceflights lengthening the problem of crewmembers immunodeficiency and the probability of allergic disease manifestation became actual. The higher risk of various pathological conditions noted in cosmonauts during space flight due to lowered immunological resistance and unnatural biological and chemical environment (autoimmune reactions, bacterial and viral autoinfections, possible allergic events etc.
View Article and Find Full Text PDFVestn Ross Akad Med Nauk
September 1998
Plasma lipid oxidation (LPO) and antioxidative system were examined in test divers who made imitation diving in the pressure chamber to the depth of 250 meters. Imitation diving showed higher iron levels, followed by a rise in the concentration of primary LPO products. There were no increases in the levels of secondary LPO products probably due to the fact that the ceruloplasmin-transferrin system released active iron from the reaction and that peroxy radicals were inactivated by SH groups.
View Article and Find Full Text PDF