Publications by authors named "A Bitti"

Key Clinical Message: Although the symptoms of accidental chlorine inhalation are typically mild, severe exposure can result in acute respiratory distress syndrome (ARDS). We present a case of pediatric ARDS due to chlorine exposure in which lung lavage and exogenous surfactant were successful in avoiding more invasive and costly treatments.

Abstract: Chlorine inhalation as a result of swimming pool chlorination accidents is relatively common.

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Objective: Vitamin D deficiency is a common public health issue worldwide. The purpose of this study was to investigate the vitamin D status and its potential determinants in children residing in Sardinia (40°N), Italy.

Methods: Children were enrolled over a 12-month period.

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Article Synopsis
  • A new prognostic model for COVID-19 progression was developed to include vaccination status and early treatment, which were missing from previous scores.
  • The study analyzed data from 1,145 patients in Sassari, revealing that older age, comorbidities, and lack of vaccination were linked to disease progression, where 29.3% of patients required supplemental oxygen.
  • Multivariate analysis identified key risk factors for progression and created an easy-to-use scoring system based on various clinical and demographic variables, enhancing the ability to predict patient outcomes.
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: Vitamin D is synthesized in the skin upon sunlight exposure, showing variations with season and latitude. We aimed to investigate the influence of age, sex, and season on vitamin D status in a large pediatric cohort during the COVID-19 pandemic period and the corresponding pre-pandemic period. : Retrospective data concerning subjects aged < 18 years were extracted anonymously from the large database of a reference laboratory hospital (Sassari, Northern Sardinia, Italy).

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Recent studies suggest that X-linked glucose-6-phosphate dehydrogenase (G6PD) deficiency entails a proinflammatory state that may increase the risk of several disease conditions. However, it is not clear how this relates to the degree of enzyme insufficiency and, in heterozygous females, to skewed inactivation of the X chromosome. This study aimed to (i) investigate the enzyme activity in a cohort of 232 subjects (54.

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