Publications by authors named "A Bisschop"

Background: Blockchain has been proposed as a critical technology to facilitate more patient-centric research and health information sharing. For instance, it can be applied to coordinate and document dynamic informed consent, a procedure that allows individuals to continuously review and renew their consent to the collection, use, or sharing of their private health information. Such has been suggested to facilitate ethical, compliant longitudinal research, and patient engagement.

View Article and Find Full Text PDF

Purpose: Degenerative changes of the lumbar spine lead in general to decrease of lumbar lordosis (LL). This change affects the overall balance of the spine, and when surgery is deemed, necessary restoration of the LL is considered. How this restoration can be achieved is a matter of controversy.

View Article and Find Full Text PDF

is a nosocomial, multidrug-resistant pathogen. Whole genome sequence studies revealed that hospital-associated isolates are clustered in a separate clade A1. Here, we investigated the distribution, integration site and function of a putative gene cluster that encodes for inositol (MI) catabolism.

View Article and Find Full Text PDF

Degenerative lumbar scoliosis presumably alters spinal biomechanics, but a lack of quantitative reference measurements of these spines exists. We aimed to assess the biomechanical properties of spines with degenerative scoliosis, and to relate these to intervertebral disc degeneration (DD) and Cobb angle. Secondly, we compared these results to previous measurements of non-scoliotic spines.

View Article and Find Full Text PDF

Staphylococcus aureus is a versatile opportunistic pathogen, causing disease in human and animal species. Its pathogenicity is linked to the ability of S. aureus to secrete immunomodulatory molecules.

View Article and Find Full Text PDF