Publications by authors named "A Bisquera"
Article Synopsis
- Pain is a significant issue for individuals with epidermolysis bullosa (EB), impacting their quality of life and identified as a priority for improved treatments.
- The Prospective EB Longitudinal Evaluation Study (PEBLES) gathered data over eight years from 61 participants to evaluate pain characteristics and treatments in different RDEB subtypes.
- Results showed that 93% of participants experienced pain, with a median background pain score of 40 and procedural pain score of 52; many did not use medication for pain management despite its severity.
Background: Recessive dystrophic epidermolysis bullosa (RDEB) is a rare inherited skin fragility disorder requiring multidisciplinary management. Information regarding costs of current standard treatment is scant.
Objectives: As part of a longitudinal natural history study, we explored the community care costs of UK patients with different forms of RDEB.
Background: Itch is common and distressing in epidermolysis bullosa (EB) but has not previously been studied in depth in different recessive dystrophic EB (RDEB) subtypes.
Objectives: As part of a prospective register study of the natural history of RDEB we explored features of itch, medications used, and correlation with disease severity and quality of life.
Methods: Fifty individuals with RDEB aged 8 years and above completed the Leuven Itch Scale (LIS) (total 243 reviews over a 7-year period).
Objective: To examine changes in lung function over time in extremely prematurely born adolescents.
Working Hypothesis: Changes in lung function during adolescence would vary by ventilation mode immediately after birth.
Study Design: Longitudinal follow-up study.
Background: Social and material deprivation accelerate the development of multimorbidity, yet the mechanisms which drive multimorbidity pathways and trajectories remain unclear. We aimed to examine the association between health inequality, risk factors and accumulation or resolution of LTCs, taking disease sequences into consideration.
Methods: We conducted a retrospective cohort of adults aged 18 years and over, registered between April 2005 and May 2020 in general practices in one inner London borough ( = 826,936).