Publications by authors named "A Bille"

: Significant intraoperative and postoperative blood loss are rare but possibly life-threatening complications after lung resection surgery either during open or minimally invasive procedures. Microporous Polysaccharide Haemospheres (ARISTA™AH) have demonstrated time-efficient haemostasis, lower postoperative blood volumes and a lower blood transfusion requirement, without any identified adverse events across other specialities. The primary aim of our study was to evaluate the impact of ARISTA™AH on short-term postoperative outcomes in thoracic surgery.

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Introduction: Thymomas and thymic carcinomas are rare anterior mediastinal tumours, accounting for 0.2-1.5% of all cancers.

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NKG2D ligands (NKG2DLs) are broadly expressed in cancer. To target these, we describe an adaptor chimeric antigen receptor (CAR) termed NKG2D/Dap10-12. Herein, T cells are engineered to co-express NKG2D with a fusion protein that comprises Dap10 joined to a Dap12 endodomain.

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Objectives: Minimally invasive thymectomy is an accepted approach for early-stage thymic epithelial neoplasia, reducing pain and length of stay compared with open surgery. In this study, we compare robotic and video-assisted thymectomy to assess pathological resection status, overall and disease-free survival.

Methods: Data were retrieved from the European Society of Thoracic Surgeons prospectively maintained thymic database.

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Article Synopsis
  • Stage IIIA-N2 non-small cell lung cancer (NSCLC) has low survival rates and lacks a standardized treatment, making patient management difficult.
  • This study analyzed 142 patients to assess overall survival (OS) and disease-free survival (DFS), finding the median OS to be 31 months, with no significant differences between treatment methods.
  • The results emphasize the need for personalized treatment plans and collaborative decision-making among healthcare professionals, with future research aimed at new therapies and multi-centre trials.
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