Suzuki-Miyaura/Mizoroki-Heck coupling cascade to access 2,2'-bifunctionalized biaryls.

Biaryl motifs are essential structural features in several drugs and functional molecules. Cyclic diaryliodonium has been scarcely explored as a bifunctional agent compared to ring opening and annulation reactions. Herein, a three-component cascade approach is developed to synthesize bifunctionalized biaryls employing cyclic diaryliodoniums as a biarylating agent.

Comparison of Direct Laryngoscopy With McCoy Blade and BPL Video Laryngoscopy for Intubation in Patients Undergoing Elective Cervical Spine Surgery.

Background: For patients having cervical spine instability, stabilization of the neck is crucial to prevent further damage to the spinal cord, which can make laryngoscopy challenging. Specialized tools like McCoy blade direct laryngoscope (Surgitech, India) and BPL video laryngoscope (BPL Medical Technologies Pvt. Ltd.

Effects of Stroke Nurse-Led Acute Stroke Management on Treatment Time Benchmarks, Intravenous Thrombolysis Rates, and Patient Outcomes: A Systematic Review and Meta-Analysis.

Introduction: Multidisciplinary stroke teams, including a stroke nurse, prove effective in delivering optimal acute ischemic stroke (AIS) management. This systematic review and meta-analysis critically synthesize existing studies to assess the impact of stroke nurse involvement on treatment time benchmarks and patient outcomes.

Method: Data from various databases constituted the primary sources of literature, and the risk of bias and article quality were evaluated using relevant tools.

The role of industry 4.0 enabling technologies for predicting, and managing of algal blooms: Bridging gaps and unlocking potential.

Recent advancements in data analytics, predictive modeling, and optimization have highlighted the potential of integrating algal blooms (ABs) with Industry 4.0 technologies. Among these innovations, digital twins (DT) have gained prominence, driven by the rapid development of artificial intelligence (AI) and machine learning (ML) technologies, particularly those associated with the Internet of Things (IoT).