Pinpointing sources of pollution using citizen science and hyperlocal low-cost mobile source apportionment.

Currently, methodologies for the identification and apportionment of air pollution sources are not widely applied due to their high cost. We present a new approach, combining mobile measurements from multiple sensors collected from the daily walks of citizen scientists, in a high population density area of Birmingham, UK. The methodology successfully pinpoints the different sources affecting the local air quality in the area using only a handful of measurements.

Mn vs Co substitution into β-TCP: Structural details and bone cells response.

This work investigated the range of substitution of two biologically relevant ions, namely Mn and Co, into the structure of β-tricalcium phosphate, as well as their influence on bone cells response. To this aim, β-TCP was synthesized by solid state reaction in the presence of increasing amount of the substituent ions. The results of the X-ray diffraction analysis reveal that just limited amounts of these ions can enter into the β-TCP structure: 15 at% and 20 at% for cobalt and manganese, respectively.

Regulation of osteogenesis and angiogenesis by cobalt, manganese and strontium doped apatitic materials for functional bone tissue regeneration.

Strontium, cobalt, and manganese ions are present in the composition of bone and useful for bone metabolism, even when combined with calcium phosphate in the composition of biomaterials. Herein we explored the possibility to include these ions in the composition of apatitic materials prepared through the cementitious reaction between ion-substituted calcium phosphate dibasic dihydrate, CaHPO·2HO (DCPD) and tetracalcium phosphate, Ca(PO)O (TTCP). The results of the chemical, structural, morphological and mechanical characterization indicate that cobalt and manganese exhibit a greater delaying effect than strontium (about 15 at.

Biophysical characterization of the phase separation of TDP-43 devoid of the C-terminal domain.

Background: Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-TDP), amyotrophic lateral sclerosis (ALS) and limbic-predominant age-related TDP-43 encephalopathy (LATE) are associated with deposition of cytoplasmic inclusions of TAR DNA-binding protein 43 (TDP-43) in neurons. One complexity of this process lies in the ability of TDP-43 to form liquid-phase membraneless organelles in cells. Previous work has shown that the recombinant, purified, prion-like domain (PrLD) forms liquid droplets in vitro, but the behaviour of the complementary fragment is uncertain.

The Role of WO Nanoparticles on the Properties of Gelatin Films.

Gelatin films are very versatile materials whose properties can be tuned through functionalization with different systems. This work investigates the influence of WO nanoparticles on the swelling, barrier, mechanical, and photochromic properties of gelatin films. To this purpose, polyvinylpirrolidone (PVP)-stabilized WO nanoparticles were loaded on gelatin films at two different pH values, namely, 4 and 7.