Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet.

Background And Objective: Accurate extraction of retinal vascular components is vital in diagnosing and treating retinal diseases. Achieving precise segmentation of retinal blood vessels is challenging due to their complex structure and overlapping vessels with other anatomical features. Existing deep neural networks often suffer from false positives at vessel branches or missing fragile vessel patterns.

"Teledentistry" using a mobile app (Telesmile) to improve oral health among the visually impaired and hearing-impaired populations in Saudi Arabia: a randomized controlled study.

Objective: To assess the efficacy of a "teledentistry" method using a mobile app (Telesmile) in enhancing knowledge of oral health conditions and oral hygiene practices among the blind and deaf populations in Jazan Province in Saudi Arabia.

Methods: A randomized parallel design controlled study was conducted among 50 blind and 50 deaf subjects between the ages of 12-18 years, randomly chosen from blind and deaf schools. The participants were selected based on the inclusion and exclusion criteria.

Equilibrium and Nonequilibrium Ensemble Methods for Accurate, Precise and Reproducible Absolute Binding Free Energy Calculations.

Free energy calculations for protein-ligand complexes have become widespread in recent years owing to several conceptual, methodological and technological advances. Central among these is the use of ensemble methods which permits accurate, precise and reproducible predictions and is necessary for uncertainty quantification. Absolute binding free energies (ABFEs) are challenging to predict using alchemical methods and their routine application in drug discovery has remained out of reach until now.

Plaque Removal and Gingival Bleeding Using Biodegradable Toothbrushes: Salvadora persica, Bamboo, and Nylon: A Comparative Study.

BACKGROUND There is little information available comparing eco-friendly products versus traditional plastic-based oral care implements. Therefore, this study was conducted to compare the plaque removal efficacy and bacterial contamination of biodegradable miswak (S. persica) toothbrushes with bamboo toothbrushes and conventional toothbrushes.

PARP Pioneers: Using BRCA1/2 Mutation-targeted Inhibition to Revolutionize Breast Cancer Treatment.

Breast Cancer stands on the second position in the world in being common and women happen to have it with high rate of about five-folds around the world. The causes of occurrence can matter with different humans be it external factors or the internal genetic ones. Breast cancer is primarily driven by mutations in the BRCA1 and BRCA2 susceptibility genes.