Progression of valve heart disease in a cohort of patients undergoing renal replacement therapy.

Introduction: Cardiovascular disease is an important cause of death among patients with chronic kidney disease (CKD). Valve calcification is a predictor of cardiovascular mortality and coronary artery disease.

Objective: To assess heart valve disease frequency, associated factors, and progression in CKD patients.

Association between hyperuricemia and hypertension: a case-control study.

Objective: The aim of this study was to evaluate the association between hyperuricemia and systemic arterial hypertension.

Methods: This was a case-control study where individuals aged >18 years were included, who were divided into hypertensive and non-hypertensive groups, excluding those with incomplete information in medical records or with the chronic kidney disease epidemiology collaboration <60 mL/min/1.73 m³.

Influence of the partial substitution of fine aggregate by granite powder in mortar on the process of natural carbonation.

This article presents an evaluation of the influence on the natural carbonation process of the use of granite cutting residue as a replacement for fine aggregate in mortars. The methodology adopted consisted of replacing the fine aggregate with granite cutting residue, analysing the carbonation depth with the aid of an experimental planning matrix of 2 + 3 repetitions at the central point. The influence of the exposure time, the percentage of residue in the mixture, and the particle size of the residue used were evaluated.

GLA Gene Mutation in Hypertrophic Cardiomyopathy with a New Variant Description: Is it Fabry's Disease?

Background: Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations in the alpha galactosidase A gene (GLA) that lead to the enzymatic deficiency of alpha galactosidase (α-Gal A), resulting in the accumulation of globotriaosylceramide (Gb3) and globotriaosylsphingosine (lyso-Gb3), causing multiple organ dysfunctions.

Objective: To perform GLA gene screening in a group of patients with echocardiographic diagnosis of hypertrophic cardiomyopathy (HCM).

Methods: a cross-sectional study was conducted with HCM patients from a university hospital.