Dementia Care Research and Psychosocial Factors.

Background: Stress associated with caregiving for a person with Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/RD) has negative health implications. However, little is known about the implications of stress on non-Hispanic Black (NHB) informal male caregivers. This study aims to examine the relationship between sleep, depression, and cognitive function in a sample of NHB informal male caregivers in the metropolitan Washington, D.

Date seeds polysaccharides as novel capping agents for selenium nanoparticles: Synthesis, characterization, stability, biological activities, and gut microbiota modulation.

Date seed polysaccharides were utilized to synthesize selenium nanoparticles (MPS-NP) through a redox reaction involving sodium selenite and ascorbic acid. Characterization of MPS-NP showed a uniform, amorphous, spherical shape with a particle size of 89.2 nm, remaining stable for 42 days.

Tubulin-Binding Region Modulates Cholesterol-Triggered Aggregation of Tau Proteins.

A hallmark of Alzheimer disease (AD) and tauopathies, severe neurodegenerative diseases, is the progressive aggregation of Tau, also known as microtubule-associated Tau protein. Full-length Tau, also known as 2N4R, contains two N-terminal inserts that bind to tubulin. This facilitates the self-assembly of tubulin simultaneously enhancing stability of cell microtubules.

Demographic and regional patterns of epilepsy-related mortality in the USA: Insights from CDC WONDER data.

Background: Epilepsy poses significant challenges globally, with varied clinical, social, and economic impacts. Despite advances in treatment, epilepsy-related mortality remains a concern. This study aimed to analyze the demographic and regional distributions of epilepsy-related mortality in the United States (U.

Medical Therapy Alone for Ommaya Reservoir-Associated Bacterial Meningitis: When It Works and When It Fails.

Background And Objectives: Administration of intraventricular chemotherapy through Ommaya reservoir is indicated for certain forms of leptomeningeal disease. However, ventricular reservoirs carry a substantial risk of infection. The conventional approach to managing reservoir-associated infections involves removal of the reservoir and systemic antibiotic therapy, but this strategy necessitates additional procedures to remove and subsequently replace the device.