Efficacy and Safety of Systemic Thrombolysis and Catheter-Directed Therapy in Pulmonary Embolism: A Narrative Review.

Pulmonary embolism (PE) is the third most frequent cause of acute cardiovascular presentation after myocardial infarction and stroke. The treatment approach for PE consists of hemodynamic and respiratory support, anticoagulation, reperfusion treatment, and vena cava filters. Reperfusion treatment consists of systemic thrombolysis (recombinant tissue-type plasminogen activator, streptokinase, and urokinase); percutaneous catheter-directed therapy (CDT); and surgical embolectomy.

Management of Keloids and Hypertrophic Scars.

Keloid and hypertrophic scars are a result of aberrant wound healing responses within the reticular dermis. They are thought to be secondary to the formation of a disorganized extracellular matrix due to excessive fibroproliferative collagen response. Prevention of these scars focuses on avoiding elective or cosmetic procedures such as piercings in patients at high risk, reducing tension across the lesion, and decreasing the inflammatory response.

Temporal gravimetry, campaign and permanent GNSS, and interferometric radar techniques: A comparative approach to quantifying land deformation rates in coastal Texas.

Land subsidence and local sea-level rise are well-known on-going hazards that negatively impacting coastal regions, exacerbating coastal flooding, threatening infrastructure stability, accelerating erosion, and amplifying the risks of inundation and property damage. This study used four techniques to quantify land deformation rates in the Texas Coastal Bend region and to investigate the controlling factors on two different spatiotemporal scales: (1) local scale, where biweekly temporal gravity and campaign Global Navigation Satellite System (GNSS) measurements were acquired at six locations over 2 years (October 2020-September 2022); and (2) regional scale, where vertical displacement time series were extracted from the Interferometric Synthetic Aperture Radar (InSAR) and 15 permanent GNSS stations over 5 years (January 2017-November 2021). The observed inconsistency between land deformation rates derived from gravity (range: -33.

An island of receptor-like genes at the Rrs13 locus on barley chromosome 6HS co-locate with three novel sources of scald resistance.

Three Hordeum spontaneum-derived resistances (referred to as 145L2, 41T1 and 40Y5) have demonstrated long-term effectiveness against barley scald, caused by Rhynchosporium commune, in western Canada. Genetic mapping of these resistances in three populations, and the use of five barley genome assemblies, revealed they co-located to a narrowly defined 0.58-1.

Integrating targeted genetic markers to genotyping-by-sequencing for an ultimate genotyping tool.

New selection methods, using trait-specific markers (marker-assisted selection (MAS)) and/or genome-wide markers (genomic selection (GS)), are becoming increasingly widespread in breeding programs. This new era requires innovative and cost-efficient solutions for genotyping. Reduction in sequencing cost has enhanced the use of high-throughput low-cost genotyping methods such as genotyping-by-sequencing (GBS) for genome-wide single-nucleotide polymorphism (SNP) profiling in large breeding populations.