Publications by authors named "A Bassols"
Fecal lactoferrin and fecal calprotectin have been proposed as biomarkers of intestinal inflammation in several animal species. The main objectives of this work were to validate an analytical procedure for the measurement of lactoferrin in calf feces, to study the correlation between lactoferrin and calprotectin concentrations, and to evaluate the influence of fecal water content in the determination of these proteins. This knowledge is essential for effectively using these biomarkers in young calves exposed to inflammatory gastrointestinal diseases.
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Lancet Psychiatry
September 2024
Article Synopsis
- Obesity contributes to age-related neurodegenerative diseases by causing mitochondrial dysfunction and oxidative damage to proteins, mainly through lipoxidation due to high unsaturated fatty acid levels.
- In a study using a pig model, researchers found that obesity increased the biomarker malondialdehyde-lysine (MDAL) by 34% in the brain, with positive correlations to body weight and LDL cholesterol levels.
- Including omega-3 fatty acids and probiotics in a high-fat diet can prevent oxidative changes in the brain, indicating that dietary choices may play a role in preventing neurodegenerative conditions.
The concentration of calprotectin in feces is a well-studied marker of gastrointestinal inflammation in humans. However, little is known about fecal calprotectin in farm animals. In this work, we have validated an immunoturbidimetric method for fecal calprotectin (Bühlmann fCAL® turbo assay, Schönenbuch, Switzerland) in porcine and bovine fecal samples.
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