Publications by authors named "A Barbato"
Cardiovascular diseases (CVDs) cause about 30% of deaths worldwide, increasing social and economic burden in our societies. Although the treatment of the canonical cardiovascular risk factors has reduced the impact of CVDs on morbidity and mortality in the past few years, they continue to represent a major health problem. The definition of the biological properties of the bone-heart axis has led to new insights in the pathogenesis of CVDs; hence, the aim of this review is to try to elucidate the role of this axis on the susceptibility to CVDs.
View Article and Find Full Text PDFPlesiomonas shigelloides infection in newborn: case report and literature review.
Childs Nerv Syst
November 2024
Introduction: Plesiomonas shigelloides is a gram-negative bacillus causing foodborne infection due to contaminated seafood leading to gastroenteritis and dysentery. Instances of neonatal infection attributed to Plesiomonas shigelloides are exceedingly rare, and available literature is sparse, with only 15 reported cases to our knowledge. Central nervous system (CNS) involvement is reported, presenting severe meningoencephalitis in some cases.
View Article and Find Full Text PDFArticle Synopsis
- - Lysosomal storage diseases (LSDs) are rare metabolic disorders caused by lysosomal dysfunction, leading to harmful substance accumulation and affecting multiple organs.
- - Discussions among Italian experts highlighted the importance of early diagnosis, better transition from pediatric to adult care, and a multidisciplinary approach to improve patient management.
- - Key solutions include newborn screening, telemedicine for territorial management, actively involving patient associations, and creating specialized teams, along with investing in training and resources to enhance overall care.
: Thyroid nodules are a very common finding, mostly benign but sometimes malignant, and thus require accurate diagnosis. Ultrasound and fine needle biopsy are the most widely used and reliable diagnostic methods to date, but they are sometimes limited in addressing benign from malignant nodules, mainly with regard to ultrasound, by the operator's experience. Radiomics, quantitative feature extraction from medical images and machine learning offer promising avenues to improve diagnosis.
View Article and Find Full Text PDFBackground: Continuous antipsychotic (AP) therapy is crucial for managing psychotic disorders, and its early interruption reflects the drug's failure. Real-world epidemiological research is essential for confirming experimental data and generating new research hypotheses.
Methods: The persistence of oral APs in a large population sample from 2000 to 2021 was analyzed by comparing AP prescriptions over this period across four Italian provinces, using dispensing data linked via a record-linkage procedure among regional healthcare utilization databases.