Publications by authors named "A Barbarossa"
Tricuspid regurgitation (TR) poses a significant healthcare burden and is a major concern for patients who experience debilitating symptoms and face a poorer prognosis. Cardiologists are showing renewed interest in TR, as the previous belief that it was merely a bystander of left-sided heart disease has evolved. As a result, more transcatheter techniques addressing TR are emerging.
View Article and Find Full Text PDFBackground: In lung transplantation (LuTx), various ischemic phases exist, yet the rewarming ischemia time (RIT) during implantation has often been overlooked. During RIT, lungs are deflated and exposed to the body temperature in the recipient's chest cavity. Our prior clinical findings demonstrated that prolonged RIT increases the risk of primary graft dysfunction.
View Article and Find Full Text PDFThe emergence and spread of drug-resistant pathogens, resulting in antimicrobial resistance, continue to compromise our capability to handle commonly occurring infectious diseases. The rapid global spread of multi-drug-resistant pathogens, particularly systemic fungal infections, presents a significant concern, as existing antimicrobial drugs are becoming ineffective against them. In recent decades, there has been a notable increase in systemic fungal infections, primarily caused by species, which are progressively developing resistance to azoles.
View Article and Find Full Text PDFArticle Synopsis
- - Waste from the agri-food chain, specifically olive oil wastewater, can be transformed into a valuable supplement enriched with hydroxytyrosol (HT), which might help prevent cardiovascular diseases.
- - Although it doesn't significantly change heart and blood vessel functions in "ex vivo" studies, it effectively removes harmful reactive oxygen species and reduces inflammatory markers in "in vitro" tests.
- - The extract also shows potential for lowering arterial stiffness, which could lead to reduced blood pressure and improved heart function, suggesting its dual role in cardiovascular health and infection prevention.
Article Synopsis
- - Cadmium (Cd) is toxic to cells, causing oxidative stress and damage, prompting research into natural antioxidants to help counteract these effects.
- - This study specifically looked at the protective abilities of melatonin (MLT), Vitamin E (VitE), and Trolox against Cd toxicity in various human cell lines, using the MTT assay to measure cell viability.
- - Results showed Vitamin E was the most effective at providing protection, but MLT also significantly reduced toxicity, especially at higher levels of Cd exposure, indicating both could be useful in reducing oxidative stress from Cd.