Publications by authors named "A Ballaz-Quincoces"
Article Synopsis
- Detecting hidden cancers in patients with unexplained venous thromboembolism (VTE) is challenging, and this study sought to explore how coagulation-related biomarkers could help.
- A study involving 214 patients with unprovoked VTE measured several biomarkers at diagnosis, finding that sP-selectin levels were significantly higher in patients with occult cancer.
- Combining high levels of sP-selectin and D-dimer can potentially identify occult cancer with up to 91% specificity, indicating these biomarkers may be useful in clinical settings, although more research is needed.
Article Synopsis
- Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious complication that can occur after acute pulmonary embolism (PE), and this study evaluated a screening program for its detection among PE survivors.
- The study involved contacting patients diagnosed with acute PE two years prior to assess for symptoms like dyspnoea, leading to further testing for CTEPH diagnosis.
- The results showed that the symptom screening led to a significant increase in CTEPH diagnoses, highlighting the importance of follow-up protocols for better patient outcomes.
Article Synopsis
- Anemia is a common issue among cancer patients, negatively affecting their quality of life (QoL) and related symptoms, though its exact impact has been unclear due to varying definitions in past studies.
- Researchers conducted a detailed analysis using specific QoL questionnaires to assess the impact of anemia on cancer patients within a multicenter study from 2015-2018, which included 365 participants.
- Results showed that cancer patients with anemia reported significantly lower global health status and more severe symptoms compared to those without anemia, indicating a clinically and statistically worse QoL for anemia sufferers.
Background: The relationship between cancer and venous thromboembolic disease (VTD) are complex because the activated coagulation factors are not only involved in thrombosis but also in malignant processes, such as angiogenesis and metastasis.
Objective: To compare phenotypes of extracellular vesicles (EVs), and levels of D-dimer, soluble P-selectin (sP-selectin) and antigenic tissue factor (TF) between unprovoked VTD patients, who did not develop cancer during one-year follow-up, and those with advanced stage of cancer but not associated with VTD.
Methods: A prospective study in which we included 138 unprovoked VTD patients and 67 advanced cancer patients, who did not develop thrombosis.
A Case-Control Analysis of the Impact of Venous Thromboembolic Disease on Quality of Life of Patients with Cancer: Quality of Life in Cancer (Qca) Study.
Cancers (Basel)
December 2019
Although there is published research on the impact of venous thromboembolism (VTE) on quality of life (QoL), this issue has not been thoroughly investigated in patients with cancer-particularly using specific questionnaires. We aimed to examine the impact of acute symptomatic VTE on QoL of patients with malignancies. This was a multicenter, prospective, case-control study conducted in patients with cancer either with (cases) or without (controls) acute symptomatic VTE.
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