Aims: To determine the utility of serial cardiac magnetic resonance (CMR) imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis (RP), compared with C-reactive protein (CRP) assay alone.
Methods And Results: In 2018-21, we enrolled 18 (14.5 ± 1.
Engineers and scientists are increasingly interested in clean energy options to replace fossil fuels in response to rising environmental concerns and dwindling fossil fuel resources. There has been an increase in the installation of renewable energy resources, and at the same time, conventional energy conversion systems have improved in efficiency. In this paper, several multi-generation systems based on geothermal energy are modeled, assessed, and optimized which employ an organic Rankine cycle and a proton-exchange membrane electrolyzer subsystem in five different configurations.
View Article and Find Full Text PDFIntroduction: Anomalous aortic origin of coronary artery (AAOCA) is the second leading cause of sudden cardiac death in children and young adults. Intramural-interarterial course is the most frequent anatomic variation and coronary unroofing is widest adopted for surgical management. Symptoms recurrence is described regardless of the technique used.
View Article and Find Full Text PDFFoetal ductus arteriosus (DA) constriction can be found in complex foetal heart malformations, but rarely as an isolated defect. Although many cases of DA constriction are usually related to Non-steroidal Anti-Inflammatory Drugs (NSAIDs) maternal intake, other causes remain without an established aetiology and are referred to as idiopathic. Recently, a wide range of risks factors or substances (polyphenol-rich foods intake, naphazoline, fluoxetine, caffeine and pesticides) showed a definitive effect upon the pathway of inflammation, causing DA constriction.
View Article and Find Full Text PDFObjective: To examine the echocardiographic changes and quality of life (QoL) after surgical unroofing of myocardial bridges (MBs) involving the left anterior descending (LAD) coronary artery compared with optimal medical therapy (OMT).
Methods: Twenty-two patients (median age, 24 years; interquartile range, 16-40 years) with MBs of the LAD artery and exertional angina from 2018 to 2019 were retrospectively analyzed. Twelve patients underwent OMT and 10 underwent surgery.