Effect of remdesivir on mortality and the need for mechanical ventilation among hospitalized patients with COVID-19: real-world data from a resource-limited country.

Objectives: Georgia introduced remdesivir for the treatment of COVID-19 in December 2020. We evaluated the real-world effect of remdesivir on mortality and the need for mechanical ventilation among inpatients with COVID-19.

Methods: The study included 346 remdesivir recipients and 346 controls not receiving remdesivir selected through propensity score matching based on age, gender, presence of any chronic comorbid condition, and oxygen saturation at admission.

ELECTROPHYSIOLOGICAL CORRELATES OF MASTICATORY MUSCLES IN NASAL AND ORONASAL BREATHING MODES.

Aim of the study was to assess electrophysiologic characteristics of masticatory muscles, right and left temporalis and right and left masseter, in nasal and oronasal breathing modes. The study was conducted on the group of 30 female volunteers who were referred to the clinic for orthodontic problems. Conflict of interests was ruled out.

ELECTROPHYSIOLOGICAL CORRELATES OF MASTICATORY MUSCLES IN NASAL AND ORAL BREATHING MODES.

Type of breathing (nasal, oral, oronasal) can turn out to be a causative factor for (or result of) orthodontic anomalies alongside the respiratory-metabolic disorders. Consequently, assessment of functional characteristics of the masticatory apparatus, which differ in oral and nasal breathing modes, could be of interest for the evaluation of the degree of orthodontic dysfunction and formation of an effective individualized treatment plan. Aim of the study was to assess electrophysiologic characteristics of the masticatory muscles bilaterally in nasal and oral breathing modes.