Publications by authors named "A Bagri"
Therapy resistance in prostate cancer: mechanism, signaling and reversal strategies.
Explor Target Antitumor Ther
August 2024
Prostate cancer (PC) depicts a major health challenge all over the globe due to its complexities in the treatment and diverse clinical trajectories. Even in the advances in the modern treatment strategies, the spectrum of resistance to the therapies continues to be a significant challenge. This review comprehensively examines the underlying mechanisms of the therapy resistance occurred in PC, focusing on both the tumor microenvironment and the signaling pathways implicated in the resistance.
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- Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can cause symptoms from mild to severe, with convalescent COVID plasma (CCP) showing potential therapeutic benefits in some patients by reducing COVID-19 severity.
- The study tested pooled lyophilized CCP from recovered patients to see if it maintained the ability to neutralize the virus, comparing antibody levels and effectiveness before and after processing.
- Results showed that the neutralizing antibodies in the lyophilized CCP had minimal loss of efficacy after treatment, indicating it could still be a valuable therapeutic option.
Background: Excessive sodium (Na) and insufficient potassium (K) intake contribute to a high risk of cardiovascular events. Morocco lacks data on actual Na and K intake in adults. We estimated mean Na and K intake in a Moroccan population of adults residing in the Northwest region using 24-h urinary excretion and examined their association with blood pressure (BP).
View Article and Find Full Text PDFLight-Controlled Magnetoelastic Effects in Ni/BaTiO Heterostructures.
ACS Appl Mater Interfaces
April 2023
Magnetoelastic and magnetoelectric coupling in the artificial multiferroic heterostructures facilitate valuable features for device applications such as magnetic field sensors and electric-write magnetic-read memory devices. In ferromagnetic/ferroelectric heterostructures, the intertwined physical properties can be manipulated by an external perturbation, such as an electric field, temperature, or a magnetic field. Here, we demonstrate the remote-controlled tunability of these effects under visible, coherent, and polarized light.
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- The study examines the efficacy of donated COVID-19 convalescent plasma (dCCP) in hospitalized adults with COVID-19 pneumonia, focusing on factors like antibody titers and patient characteristics.
- The results showed that 85% of the dCCPs contained neutralizing antibodies, and while the transfusion didn't significantly affect survival rates, no adverse events were reported among dCCP recipients.
- The findings highlight the variability in antibody responses among dCCP recipients, suggesting the need for controlled trials to utilize well-characterized dCCP with appropriate assays.