Publications by authors named "A Badorff"

Article Synopsis
  • - Spontaneous coronary artery dissection (SCAD) is a rare but significant cause of acute coronary syndrome (ACS), and its diagnosis may be underestimated due to limited knowledge about the condition.
  • - A study analyzing SCAD cases from 1997 to 2021 showed a significant increase in incidence both overall and in relation to ACS, highlighting trends such as shorter lesions and a shift toward conservative treatment methods.
  • - Despite a stable major adverse cardiac event (MACE) rate of 24%, there was a reduction in the need for intensive care, indicating the benefits of improved management strategies for SCAD patients.
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Apoptosis is a central host defense mechanism to eliminate virus-infected cells. Activation of NF-kappaB suppresses apoptosis following some types of stimulation in vitro. To test the physiological importance of this pathway in vivo, we studied murine encephalomyocarditis virus (EMCV) infection in mice and cell lines defective in NF-kappaB1 (p50) signaling.

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Three adenine nucleotide translocase isoforms (ANT1, ANT2 and ANT3) are coded by different genes. The relative amounts of the three ANT isoform mRNAs were determined in detail in various human tissues. ANT isoforms were co-expressed in all tested tissues revealing tissue-specific transcription patterns.

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