[Ten years of clinical experience with clozapine about 170 patients].

The authors describe a clinical trial of 170 patients who received clozapine over a ten year period between September 1989 and September 1999. It is a retrospective study, describing individual responses. Each patient was his own control before and with treatment.

[Psychodynamic understanding of anxiety].

Anxiety as a state of arousal--Is it the same thing in pathology as in the ordinary experience of every human being? The outward show of anxiety is evidently the same, but what exactly do we mean by anxiety? Anxiety is one of the less welcome sides of man's superiority over the animals, stemming from a consciousness of one's own being, the freedom to make choices about the future and to plan ahead, the need to develop one's own personality, to create an identity for oneself in an environment where the means for such self-fulfillment appear always to be insufficient. This existential anxiety becomes pathological through symptoms; it manifests a specific weakness for each psychopathological structure. There are two different, but not irreconcilable approaches to understanding the mechanisms of anxiety: one biodynamic , the other psychodynamic.