Publications by authors named "A BLANCHET"
Article Synopsis
- - Fabry disease (FD) is a rare genetic disorder linked to the GLA gene and is marked by a range of symptoms affecting various organs, often signaled by chronic pain.
- - Two studies were conducted to determine the prevalence of FD in chronic pain patients, testing alpha-galactosidase A activity in men and analyzing the GLA gene in women.
- - The findings indicated that FD's prevalence in this group is about 1 in 1000 individuals, suggesting that while routine screening for FD in chronic pain patients is not essential, awareness of its symptoms is crucial for diagnosis, especially with family histories of the disease.
Objective: The aim of this study was to investigate the physicochemical stability of morphine-bupivacaine-ziconotide mixtures used in intrathecal analgesia in polypropylene syringes and intrathecal pumps.
Materials And Methods: The stability study method was conceived according to International Council for Harmonisation guidelines. For propylene syringes, six different mixtures of morphine-bupivacaine and ziconotide were assessed over seven days.
Cooperation and deception through stigmergic interactions in human groups.
Proc Natl Acad Sci U S A
October 2023
Stigmergy is a generic coordination mechanism widely used by animal societies, in which traces left by individuals in a medium guide and stimulate their subsequent actions. In humans, new forms of stigmergic processes have emerged through the development of online services that extensively use the digital traces left by their users. Here, we combine interactive experiments with faithful data-based modeling to investigate how groups of individuals exploit a simple rating system and the resulting traces in an information search task in competitive or noncompetitive conditions.
View Article and Find Full Text PDFMeasurements of neutrino oscillation parameters from the T2K experiment using protons on target.
Eur Phys J C Part Fields
September 2023
Article Synopsis
- - The T2K experiment reports enhanced measurements of neutrino oscillation parameters through new proton-on-target (POT) neutrino data, significantly improving analysis methods with a major focus on the near detector's new selection procedures.
- - This analysis is the first to utilize data from the NA61/SHINE experiment, helping to refine the neutrino flux model and enhance the neutrino interaction model by incorporating new nuclear effects.
- - Both frequentist and Bayesian approaches indicate a preference for normal mass ordering and a nearly maximal CP-violating phase, with notable exclusions and constraints on certain parameters aligning with past T2K studies.
Study hypothesis : Implementation of a new pathway dedicated to septic patients within the emergency department (ED) would improve early management, organ dysfunction, and outcome. Methods: During phase 1, all consecutive adult patients with infection and qualifying quick Sequential Organ Failure Assessment (qSOFA) score upon ED admission were managed according to standards of care. A multifaceted intervention was then performed (implementation phase): educational program, creation of a sepsis alert upon ED admission incorporated in the professional software, together with severity scores and Surviving Sepsis Campaign (SSC) bundle reminders, and dedication of two rooms to the management of septic patients (sepsis unit).
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