Feasibility of conducting a large, randomized controlled trial for STD counseling in a managed care setting.

Background: Screening for, and prevention of, sexually transmitted diseases requires access to the adolescent, which is often difficult. The primary care visit can offer an opportunity to provide prevention counseling to adolescents. The objective of this study was to determine the feasibility of conducting a large randomized, controlled trial of sexually transmitted diseases counseling intervention in a managed care setting.

Parent and student preferences for services in a school-based clinic.

As a component of program planning for a school-based clinic in a suburban high school, a sample of 199 students and 196 parents were surveyed about preferences for health services. Parents and students were asked about health services desired and level of interest. Student overall interest in health services was less than parent interest, although both groups indicated at least a moderate level of interest.

Transmission of Plasmodium gallinaceum by adult Aedes aegypti infected as larvae.

Transmission of Plasmodium gallinaceum to chickens by adult mosquitoes eclosed from larvae that consumed infected adult mosquitoes was investigated. No malarial infections were observed in chicks fed on by mosquitoes that eclosed from larvae that had consumed crushed infected adult mosquitoes. Where cadavers with noncrushed thoraces were used, 3 of 4 chicks fed on by adult mosquitoes developed parasitemias ranging from 6 to 11% infected erythrocytes.

Plasmodium fallax: the invasion of host cells by exoerythrocytic merozoites in tissue culture.

Exoerythrocytic merozoites of Plasmodium fallax in tissue culture have been observed and photographed in time-lapse cinemicrography as they invaded new host cells. Entry into the host cells was rapid and frequently several merozoites invaded the cells in rapid succession at or near the same site. The invasion proceeded at the broad (posterior) area of the merozoites, away from a filamentous process that usually held clusters of merozoites together in rosette form.

Plasmodium fallax: phagocytosis of exoerythrocytic stages in tissue culture.

Wandering phagocytes in tissue cultures were attracted to the exoerythrocytic stages, both intracellular and extracellular, of Plasmodium fallax. They phagocytized free merozoites or schizonts that had been freed from host cells. They attempted to phagocytize large intracellular parasites.