Publications by authors named "A B Te Pas"
Article Synopsis
- Chorioamnionitis (HCA) and funisitis (FUN) are linked to preterm birth, and their combined effects can negatively influence an infant's respiratory drive after birth.* -
- A study involving 186 infants found that those with HCA and FUN had significantly lower gestational ages and birthweights compared to those without these conditions.* -
- While HCA and FUN were associated with reduced breathing effort in the first five minutes of life, subclinical HCA and FUN showed no significant impact on breathing metrics.*
The bacteria of a host's digestive tract play crucial roles in digestion and pathogen resistance. Hosts living in captivity often have more human interaction and antibiotic use, in addition to differences in diet and environment, compared to their wild counterparts. Consequently, wild and captive animals frequently harbour different bacterial communities.
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- Most very premature infants breathe at birth but often need respiratory support due to issues like chorioamnionitis, which is inflammation of the fetal membranes.
- Chorioamnionitis can release inflammatory substances that may depress the brain's respiratory drive, leading to risks of hypoxic injury in these infants.
- The review suggests that understanding how chorioamnionitis affects breathing can help develop interventions to stimulate spontaneous breathing in these infants during birth.
Background: Apnoea of prematurity (AOP) is one of the most common diagnoses among preterm infants. AOP often leads to hypoxemia and bradycardia which are associated with an increased risk of death or disability. In addition to caffeine therapy and non-invasive respiratory support, doxapram might be used to reduce hypoxemic episodes and the need for invasive mechanical ventilation in preterm infants, thereby possibly improving their long-term outcome.
View Article and Find Full Text PDFThe avian gut microbiota has been the subject of considerable recent attention, with potential implications for diverse fields such as the poultry industry, microbial ecology, and conservation. Faecal microbiotas are frequently used as a non-invasive proxy for the gut microbiota, however the extraction of high-quality microbial DNA from avian faeces has often proven challenging. Here we aimed to evaluate the performance of two DNA preservation methods (95% ethanol and RNAlater) and five extraction approaches (IndiSpin Pathogen Kit, QIAamp PowerFecal Pro DNA Kit, MicroGEM PrepGEM Bacteria Kit, ZymoBIOMICS DNA Miniprep Kit, and an in-house phase separation-based method) for studying the avian gut microbiota.
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