Publications by authors named "A B Smolianinov"

There are contradictory data concerning the influence of mesenchymal stromal cells (MSC) on immunoglobulin (Ig) production. Most of them were obtained using MSC from bone marrow. Properties of MSC from other tissues are elusive.

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This paper examines the structural and mechanical properties of composite materials based on chitosan and micro- and nanoparticles of Na-montmorillonite and possibility of application for cultivation and targeted delivery of mesenchymal stem cells and regenerative cells. It's have been shown by addition of Na-montmorillonite biomaterial acquires stability of structural and mechanical properties in the sterilization process the handling of liquid media in cell culture. In vitro studies using dermal fibroblasts and adipose tissue mesenchymal stem cells demonstrated that this material has a set of properties to ensure matrix biocompatibility.

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Telomeres are the ends of the chromosomes and represent repeated DNA sequence and protein complex. Telomeres shorten with each cell division, which limits proliferative potential of cells. There is a great progress in clinical application of telomere length now.

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The last years witnessed significant change in therapeutic and infectious pathology of man, its immunoreactivity changed, especially in elderly patients. Thus, older people show the increase of chronic infectious-inflammatory diseases, characterized by flaccid, constantly recurring course, torpid to adequate etiotopic therapy. They are caused by conventionally-pathogenic or opportunistic microbes, often with atypical biological properties, having multiple resistance to antibiotics.

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