Screening for chitinolytic activity in the bacterial strains from different Pacific Ocean regions revealed that the highly active representatives belong to the genera , , , and . The widely distributed chitinolytic species was isolated from the sea urchin . Among seventeen isolates with confirmed chitinolytic activity, only the type strain KMM 3630 and the strains of putatively new species sp.
View Article and Find Full Text PDFThe global spread of the metabolic syndrome, oncological and viral diseases forces researchers to pay increased attention to the secondary metabolites of marine hydrobionts, which often have a high therapeutic potential in the treatment of these pathologies and are effective components of functional food. The flavone luteolin (LT), as one of the most widely distributed and studied plant metabolites, is distinguished by a diverse spectrum of biological activity and a pleiotropic nature of the mechanism of action at the molecular, cellular and organismal levels. However, there is still practically no information on the spectrum of biological activity of its sulfated derivatives, which are widely represented in seagrasses of the genus Zostera.
View Article and Find Full Text PDFAn efficient -mediated genetic transformation based on the plant binary vector pPZP-RCS2 was carried out for the multiple heterologous protein production in filamentous fungus F-859 (formerly F-859). The engineered fungus was able to produce plant storage proteins of (α-zein Z19) and (albumin A1) to enrich fungal biomass by valuable nutritional proteins and improved amino acid content. The mRNA levels of and genes were significantly dependent on their driving promoters: the promoter of tryptophan synthase (P) was more efficient to express , while the promoter of translation elongation factor (P) provided much higher levels of transcript abundance.
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November 2020
Riboflavin is a crucial micronutrient that is a precursor to coenzymes flavin mononucleotide and flavin adenine dinucleotide, and it is required for biochemical reactions in all living cells. For decades, one of the most important applications of riboflavin has been its global use as an animal and human nutritional supplement. Being well-informed of the latest research on riboflavin production via the fermentation process is necessary for the development of new and improved microbial strains using biotechnology and metabolic engineering techniques to increase vitamin B2 yield.
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